Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases
نویسندگان
چکیده
منابع مشابه
The Association Between ANKRD55 rs6859219 SNP and the Risk of Multiple Sclerosis in Iranian Patients
Background: Multiple Sclerosis (MS) is a neuroinflammatory autoimmune disease of the central nervous system. ANKRD55 rs6859219 Single Nucleotide Polymorphisms (SNPs) are reported as a potential novel MS risk gene, but the biological reasons underlying this correlation are still mysterious. Objectives: This study aimed to investigate the potential association of ANKRD55 rs6859219 SNP with the r...
متن کاملNon-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.
OBJECTIVES Recently, a non-synonymous (Gly307Ser) variant, rs763361, in the CD226 gene was shown to be associated with multiple autoimmune diseases (ADs) in European Caucasian populations. However, shared autoimmunity with CD226 has not been evaluated in non-European populations. The aim of the present study is to assess the association of this single nucleotide polymorphism (SNP) with ADs in n...
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Systemic lupus erythematosus is a chronic autoimmune disease with multifactorial ethiopathogenesis. The complement system is involved in both the early and late stages of disease development and organ damage. To better understand autoantibody mediated complement consumption we examined ex vivo immune complex formation on autoantigen arrays. We recruited patients with SLE (n = 211), with other s...
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in one pole of the continuum of language learning, theoreticians and practitioners traditionally consider english as english as a second language or english as a foreign language. however, in the other pole of this continuum where english is thought of as the most effective tool for international communication, it is referred to as a lingua franca. those who favor an approach to english growing...
15 صفحه اولFamilial multiple sclerosis and association with other autoimmune diseases
Objectives Autoimmune diseases (AID) follow a complex, probably polygenic, pattern of inheritance and often cluster in families of patients with multiple sclerosis (MS). Our objective was to analyze family patterns and characteristics in families including more than one patient with MS. Materials and Methods We analyzed personal and family history of neurological, systemic, and autoimmune dis...
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ژورنال
عنوان ژورنال: Autoimmunity Reviews
سال: 2012
ISSN: 1568-9972
DOI: 10.1016/j.autrev.2011.07.007